Solo Mode is one of the most efficient and time saving features Adobe Lightroom has. If you haven't utilized this feature yet, it will indeed change your Lightroom workflow. Solo Mode is when only one panel is open at a certain time. When you click on another panel, the panel you were using before automatically closes. This is an amazing feature because you don't have to have several panels open at the same time and lessens the time of you going up and down all the panels.
To activate Solo Mode go to the dark grey area on either side of your panels, right click and then click Solo Mode. You would have to do this at every panel you want activated for its module specific. So if you want in your right Library Panel, right Develop Panel and left Develop panel, you'd have to activate it in all three.
Applying noise reduction one by one is a very time consuming process. Another trick that we use here at Modern Album Designs is sorting images by ISO and applying noise reduction in one or several batches.
First, go to your library and click Metadata on your Library Filter. On any of the 4 columns, click any of the headers on top and then click ISO Speed. You will then see all the ISO speeds of the photos in your Lightroom Catalog. You can now select all the ISO speeds you want to apply the Noise Reduction by clicking the ISO while holding the Ctrl button. Then, select all the images, go to the Detail panel in your Develop module and apply the settings you want for sharpening and noise reduction. You may want to do this in batches for images shot in 800 ISO may not need as much Noise Reduction compared to an image shot in 6400 ISO.